翻訳と辞書 Words near each other ・ Cop Shoot Cop (disambiguation) ・ Cop Shop ・ Cop Squad ・ Cop Tales 2000 ・ Cop That Shit ・ Cop this Lot ・ Cop This! ・ Cop, Saint-Louis-du-Sud, Haiti ・ Cop-Tur ・ COP1 ・ COP3 ・ Cop4 ・ COP6 ・ COP8 ・ COP9 constitutive photomorphogenic homolog subunit 5 ・ COP9 signalosome ・ COP9 signalosome complex subunit 3 ・ COPA ・ COPA (gene) ・ Copa (genus) ・ Copa Adrián C. Escobar ・ Copa Aerosur ・ Copa Agco Cordoba ・ Copa Airlines ・ Copa Airlines Colombia ・ Copa Airlines Colombia destinations ・ Copa Airlines destinations ・ Copa Airlines Flight 201 ・ Copa Aldao ・ Copa America (disambiguation) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク COP9 signalosome ： ウィキペディア英語版 COP9 signalosome COP9 (Constitutive photomorphogenesis 9) signalosome (CSN) is a protein complex with isopeptidase activity. It catalyses the hydrolysis of NEDD8 protein from the cullin subunit of Cullin-RING ubiquitin ligases (CRL). Therefore, it is responsible for CRL deneddylation – at the same time, it is able to bind denedyllated cullin-RING complex and retain them in deactivated form. COP9 signalosome thus serves as a sole deactivator of CRLs. It was found in all eukaryotic organisms including human; it was first discovered in plants. Human COP9 signalosome (total size ~350 kDa) consists of 8 subunits - CSN1, CSN2, CSN3, CSN4, CSN4, CSN5, CSN6, CSN7 (COPS7A, COPS7B), CSN8. All are essential for full function of the complex and mutation in some of them is lethal in mice.〔 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「COP9 signalosome」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.